Scientists have hailed an historic
turning point in the search for a medicine that could beat Alzheimer’s disease, after a drug-like compound was used to halt brain cell death in mice for the first time.
Although the prospect of a pill for Alzheimer’s remains a long way off, the landmark British study provides a major new pathway for future drug treatments.
The compound works by blocking a faulty signal in brains affected by neurodegenerative diseases, which shuts down the production of essential proteins, leading to brain cells being unprotected and dying off.
It was tested in mice with prion disease — the best animal model of human neurodegenerative disorders – but scientists said they were confident the same principles would apply in a human brain with debilitating brain diseases such as Alzheimer’s or Parkinson’s.
The study, published today in the journal Science Translational Medicine, was carried out at the Medical Research Council’s (MRC) Toxicology Unit at the University of Leicester — via redwolf.newsvine.com